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The role of bacterial viruses in the gut remains unclear. While the new findings demonstrate that the production of viruses reduces intestinal survival of L. The van Pijkeren laboratory developed several genome-editing tools, which allowed them to develop L.

A possible association between fructose consumption and pulmonary emphysema

They found that the normally dormant viruses of L. The next step was to investigate to what extent dietary sugars promoted virus production.


The team decided to focus on fructose because of its abundance in the food chain. Since the development of high-fructose corn syrup as a cost-efficient sweetener in the early s, average fructose consumption has increased fourfold.

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Mice were fed high-fructose diets along with L. The research team found that mice that ate fructose experienced a significant increase in the production of L. So, we basically searched the DNA sequence of L. These results predicted that L. Focusing on the metabolic pathway, the research team found that consumption of fructose and L.

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These are all components of the metabolic syndrome. In addition, fructose leads to leptin resistance, thereby setting up a positive feedback pathway in which continuous consumption is promoted. Lustig pointed out that these problems are all minimized when fructose is consumed in the form of whole fruit, since whole fruit always contains significant amounts of fiber , and fiber works to counteract the effects of fructose in a variety of ways.

Dr Lustig noted that fructose metabolism also is strikingly similar to the way in which ethanol is metabolized.

Dietary Fructose and Glucose: The Multifacetted Aspects of Their Metabolism - Google Books

He made the graphic point that a calorie can of soda and a calorie beer both lead to 90 calories reaching the liver, and that both result in the toxic by-products of VLDL cholesterol and excess free fatty acids. Excess alcohol consumption and excess fructose consumption also result in many of the same health problems. Both cause hypertension, dyslipidemia, insulin resistance, and fatty liver disease. AAP called to task. The American Heart Association AHA in recent recommendations has noted the role of added sugars in increasing the risk of heart disease.

Current AAP guidelines allow for 2 of the 4 recommended daily fruits to be consumed in the form of juice. That, he said, is unacceptable. The audience rose to its feet and applauded. He is a recent author of 42 Days to a New Life-a book that describes the importance of a balanced fat diet to prevent numerous diseases. His passion is to discover the causes of the exploding medical problems that are afflicting millions of Americans that he has witnessed firsthand during his medical career.

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USD Buy Online, Pick up in Store is currently unavailable, but this item may be available for in-store purchase. Sign in to Purchase Instantly. Overview The United States is witnessing an explosion of the metabolic syndrome.

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We have unprecedented levels of people walking around with high blood pressure, abdominal obesity, type II diabetes and high cholesterol. The healthcare system is overrun with heart disease, stroke, kidney failure, gout, fatty liver, gastroesophageal reflux disease and the complications that come with prolonged obesity.

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